I am pretty sure I once saw that suggestion, but impossible to find it. As it does have an interesting potential, allowing to knock people without killing them, I make it again:
Basically, all shot aimed to legs wouldn't be able kill the target, and would left it at -19 max (-39 for dead man walking). Combined with auto steal success on KO target, it also allows to loot someone without killing him. And when you have a doubt about someone and want to ensure your own safety, you can neutralize him without killing!