Like half of skills up there are pointless.
Skilling up is flawed.
Charisma needs to be removed.
Weapon skills are meaningless, all they do is lowering other skills and making low level players useless - making earlier critters much more difficult. Random stuff is unexciting, not always bad, but when it can be reduced to nearly-100% success rate, it seems somewhat pointless. It'd be far more interesting if proficiency in weapons would be gained another way, perhaps level1 perk or whatever. And skill could increase ability to do things with your weapons. Though it might be quite hard to adjust scaling. Because crippled is binary there's no place to increase crippling rate without touching mr Random. Skill increasing damage may not be good idea either. But with more design decisions it should be possible to use skill this way.
Barter/Speech are useless skills because of charisma.
Gambling is just plain useless.
Science is missing it's purpose because there are no computers to begin with. Though idea of "dungeoning" skill is double edged, because of the alts.
Lockpick is the same school as science, but already has it's usage, OK skill.
Repair is mediocre, though not bad to have. Repairing items is a little boring currently, and it's another chance check, though it has potential in PvE scenarios, and ability to repair items is interesting, though not well executed at the moment. (I would hate if it was use a rifle to repair another, but perhaps eating up an alloy might work, and if somebody wants use another rifle, he can science it :d)
Outdoorsman speeds up travel, which is nice, but the chance driven effect of encounter avoidance makes small amounts invested in this skill useless.
First Aid is excellent skill. It is not affecting any random event, and thus both low and high amount of skillpoint invested make this skill useful regardless.
Doctor is another random check, though at least it scale cooldown, making investment a little more interesting.
Steal is for another chapter, but otherwise it's just another random check, while it has at least one interesting related perk, the skill itself is not spectacular.
Sneak is ok as a skill, but sneaking itself is dumb. This thing scales nicely, though unfortunately it does not do anything much for small investments. Generally it just deduces the amount of skill you can invest elsewhere while increasing the need of your INT.
Ofcourse if sneak and weapon skills are changed, one must be sure that hp amounts would stay relatively the same. For sneak it'd be good if it had another secondary effect that could work well even for low skill amount. (No idea here).