Attacking NPCs in reno are terrible, they rubberband you, they waste your ammo they do everything but kill you.
The moment you're surrounded by NPCs you can do nothing but kill them and lower your rep, but wait there are even more of them waiting to jump into that spot! If you don't run out of ammo before you get out lucky you!
So now you've gotten out and 20 NPCs are following you, how do you exit? Well you run up and down the street 5 times until you get just enough range to get out the exit grid.
Reno should either be full on guarded with strong guards like NCR or not guarded at all, being swarmed and annoyed while trying to PVP is not fun.
Other towns: Why does the Den, a capture town have guards at all? same with Modoc and it's one guard, remove all the bloody guards from PVP towns.