I propose drugs and Big Guns to be nerfed.
Why not give the solo guy a chance, who doesn't have an alt for every single specific purpose.
Currently, there are 2 types of combat. Combat, and drugged combat. Drugged combat is a whole different league, and all you do is pay a few caps.
Big guns need no explanation.
You can't really use cost as a balancing feature, as paying for these things really aren't that tough whatsoever.
Most people probably disagree with me, or this has been suggested before, but I'm just throwing my 2 cents into the ring.