I used to try this long time ago. It was mostly placebo effect, but I did see some small effects with some of the files I tested. It is possible, but I think that the core of it is related to individuals, so it doesn't work with everyone.
Although, it is somewhat curious to see how the most expensive / effect ones work. Some people take them very seriously, and you can see it. But on the other hand, it does inflict a small piece of hesitation for viewers, I once saw my friend doing
Gates of Hades, and I must say that I wouldn't do it right away, atleast not without a small moment of thinking.
Conclusion: Test it with the exact suggested settings, else it will not work. You can't make your own conclusions about I-Doser in general without trying them.