I think not, Psycho do -9PE, so lets say, you have 6PE, take 2 cigarettes, 2 jet, still at one, and if you take 2 mentats only 3PE (and the psycho only is really expansive, so with the others drugs too...)... Yeah, psycho is pretty hardcore drug ;p. It would be better, if it put you at 1PE, and after you could take some drugs: still low PE but you could have around 5. Or do something like -5 or -6 PE to replace the -9.